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Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial.

Boukje C Eveleens MaarseClaus GraffJørgen K KantersMichiel Joost van EsdonkMichiel J B KemmeAliede E In 't VeldManon A A JansenMatthijs MoerlandPim Gal
Published in: British journal of clinical pharmacology (2021)
In this study, hydroxychloroquine did not affect ventricular repolarization, including the QTcF-interval and T-wave morphology, at plasma concentrations up to 200 ng/mL. Based on this analysis, hydroxychloroquine does not appear to increase the risk of QTcF-induced arrhythmias.
Keyphrases
  • left ventricular
  • heart failure
  • high glucose
  • catheter ablation
  • diabetic rats
  • drug induced
  • congenital heart disease
  • endothelial cells