Long-term antipsychotic use and brain changes in schizophrenia - a systematic review and meta-analysis.
Sanna HuhtaniskaErika JääskeläinenNoora HirvonenJukka RemesGraham K MurrayJuha VeijolaMatti IsohanniJouko MiettunenPublished in: Human psychopharmacology (2017)
Antipsychotic medication may associate with brain structure changes. More long-term follow-up studies taking into account illness severity measures are needed to make definitive conclusions.