Qi-dan-dihuang decoction ameliorates renal fibrosis in diabetic rats via p38MAPK/AKT/mTOR signaling pathway.

Liuyan KuangYanting YouJieying QiJieyu ChenXinghong ZhouShuai JiJingru ChengHiu Yee KwanPingping JiangXiaomin SunMengting SuMing WangWenxiao ChenRen LuoXiaoshan ZhaoLin Zhou

Published in: Environmental toxicology (2024)

QDD inhibits EMT and the inflammatory response through the p38MAPK and AKT/mTOR signaling pathways, thereby playing a protective role in renal fibrosis in DKD.

Keyphrases

signaling pathway
diabetic rats
epithelial mesenchymal transition
inflammatory response
pi k akt
cell proliferation
induced apoptosis
oxidative stress
liver fibrosis
toll like receptor
immune response