A Gradient of Intestinal Inflammation in Primary Sclerosing Cholangitis.

Agnes WittekBabett SteglichChristian CasarOliver SeizPhilipp HuberHanno EhlkenDominik ReherSandra WendeTanja BedkeJan KempskiMarius BöttcherCorinna BangLouise ThingholmTill KrechAnsgar W LohseGuido SauterThomas RöschAndre FrankeChristoph SchrammNicola GaglianiPenelope PelczarSamuel Huber

Published in: Inflammatory bowel diseases (2023)

We found a gradient of intestinal inflammation in the vast majority of PSC patients even in the absence of IBD. Thus, further studies evaluating the effect of anti-inflammatory therapies in PSC patients and their impact on the emergence of clinically manifest IBD and colorectal cancer development are needed.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
oxidative stress
prognostic factors
peritoneal dialysis
patient reported outcomes
case control