Clinical and MRI characteristics of multiple sclerosis in patients of Middle Eastern and North African ancestry residing in Ontario, Canada.
Estelle SeymanAshley JonesMelanie GuenetteReza VosoughiDaniel SelchenLilyana AmezcuaStefan BaralJiwon OhPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)
MENA-MS patients demonstrate higher disease severity compared to EUR-MS patients, despite having similar inflammatory measures of disease activity, with disability progression in the absence of relapses. These observations illustrate the importance of the intersections of environmental, socioeconomic, and genetic determinants in optimizing individualized MS care.
Keyphrases
- multiple sclerosis
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- disease activity
- mass spectrometry
- prognostic factors
- systemic lupus erythematosus
- rheumatoid arthritis
- healthcare
- peritoneal dialysis
- oxidative stress
- climate change
- patient reported outcomes
- dna methylation
- computed tomography
- ankylosing spondylitis
- contrast enhanced
- juvenile idiopathic arthritis