Childhood asthma and smoking exposures before conception-A three-generational cohort study.

Lennart BråbäckCaroline J LodgeAdrian J LoweShyamali C DharmageDavid OlssonBertil Forsberg

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)

Maternal but not paternal exposure to nicotine before conception was related to an increased risk of early persistent childhood asthma, but not other asthma phenotypes. Our findings are possibly consistent with a sex-specific mode of epigenetic transfer.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
smoking cessation
air pollution
gene expression
early life
cystic fibrosis