Shifting risk-stratified early prostate cancer detection to a primary healthcare setting.

Renée HogenhoutDaniël F OssesArnout R AlbertsHanne G Buizer-RijksenSebastiaan Remmers Monique J Roobol

Published in: BJU international (2022)

Multivariable risk-stratification for PCa detection using the RPCRC in a primary healthcare diagnostic facility could reduce 68% of referrals to secondary healthcare relative to the PSA threshold of 3.0 ng/mL with a high csPCa detection rate in those men biopsied. This strategy can be considered safe according to the observational data that showed low proportions of csPCa among men considered low-risk.

Keyphrases

healthcare
prostate cancer
loop mediated isothermal amplification
real time pcr
label free
radical prostatectomy
middle aged
electronic health record
big data
machine learning
artificial intelligence
data analysis