N-methyl-D-aspartic acid receptor 2A functionalized stationary phase: A reliable method for pursuing potential ligands against Alzheimer's disease from natural products.

Yuan-Yuan ChenYan XueJia-Tai YinLe-Jing QuHao-Peng LiQian LiXin-Feng Zhao

Published in: CNS neuroscience & therapeutics (2023)

In the present study, we developed a reliable method for the rapid identification of NMDA-2A ligands from natural products, which may be used as a platform for new drug discovery to generate high-quality drug candidates.

Keyphrases

drug discovery
high throughput
cognitive decline
emergency department
liquid chromatography
mass spectrometry
high resolution
bioinformatics analysis
simultaneous determination