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Polygenic Prediction of Type 2 Diabetes in Africa.

Tinashe ChikoworeKenneth EkoruMarijana VujkoviDipender GillFraser PirieElizabeth YoungManjinder S SandhuMark McCarthyCharles RotimiAdebowale AdeyemoAyesha A MotalaSegun Fatumo
Published in: Diabetes care (2022)
African American-derived PRS enhances polygenic prediction of T2D in continental Africans. Improved representation of non-European populations (including Africans) in GWAS promises to provide better tools for precision medicine interventions in T2D.
Keyphrases
  • african american
  • type diabetes
  • physical activity
  • cardiovascular disease
  • glycemic control
  • adipose tissue
  • skeletal muscle
  • genetic diversity