Assessment of DOAC in GEriatrics (ADAGE study): rivaroxaban/apixaban concentrations and thrombin generation profiles in NVAF very elderly patients.
Geoffrey Foulon-PintoCarmelo LafuenteGeorges JourdiJulien Le GuenFatoumata TallEtienne PuymiratMaxime DelrueLéa RiviereFlora KetzIsabelle Gouin-ThibaultFrançois MullierPascale GaussemEric PautasThomas LecompteEmmanuel CurisVirginie SiguretPublished in: Thrombosis and haemostasis (2022)
Our study provides original data in very elderly patients receiving DOAC in real-life setting, showing great inter-individual variability in plasma concentrations and TG parameters. Further research is needed to understand the potential clinical impact of these findings.