Assessment of DOAC in GEriatrics (ADAGE study): rivaroxaban/apixaban concentrations and thrombin generation profiles in NVAF very elderly patients.

Geoffrey Foulon-PintoCarmelo LafuenteGeorges JourdiJulien Le GuenFatoumata TallEtienne PuymiratMaxime DelrueLéa RiviereFlora KetzIsabelle Gouin-ThibaultFrançois MullierPascale GaussemEric PautasThomas LecompteEmmanuel CurisVirginie Siguret

Published in: Thrombosis and haemostasis (2022)

Our study provides original data in very elderly patients receiving DOAC in real-life setting, showing great inter-individual variability in plasma concentrations and TG parameters. Further research is needed to understand the potential clinical impact of these findings.

Keyphrases

venous thromboembolism
direct oral anticoagulants
machine learning
risk assessment
big data
human health