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Progress in Defining the Genetic Contribution to Type 2 Diabetes in Individuals of East Asian Ancestry.

Cassandra N SpracklenXueling S Sim
Published in: Current diabetes reports (2021)
Through increased sample size and power, new genetic associations with T2D were discovered in East Asian ancestry populations, often with higher allele frequencies than European ancestry populations. As we continue to generate maps of T2D-associated variants across diverse populations, there will be a critical need to expand and diversify other omics resources to enable integration for clinical translation.
Keyphrases
  • type diabetes
  • copy number
  • genome wide
  • genome wide association study
  • genetic diversity
  • glycemic control
  • insulin resistance
  • metabolic syndrome
  • dna methylation
  • skeletal muscle
  • weight loss