High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma.

Cheng-Han LinHao-Yi LiYu-Peng LiuPei-Fung KuoWen-Ching WangForn-Chia LinWei-Lun ChangBor-Shyang SheuYing-Jan WangWan-Chun HungHui-Chuan ChengYun-Chin YaoMarcus J CalkinsMichael HsiaoPei-Jung Lu

Published in: Therapeutic advances in medical oncology (2019)

CLDN4 was suggested as prognostic and a CCRT response indicator for ESCC patients. TTFD combined with CCRT has potential to improve ESCC patient's clinical outcomes in the future.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
induced apoptosis
locally advanced
peritoneal dialysis
prognostic factors
rectal cancer
squamous cell carcinoma
cell cycle arrest
current status
signaling pathway
radiation therapy
patient reported outcomes
cell death
human health
bone marrow
pi k akt