Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells.

Jiajie TuGeng TianHoi-Hung CheungWei WeiTin-Lap Lee

Published in: Stem cell research & therapy (2018)

Taken together, our results suggest that the lncRNA Gas5 plays an important role in modulating self-renewal and pluripotency of mESCs as well as iPSC reprogramming.

Keyphrases

embryonic stem cells
induced pluripotent stem cells
room temperature
long non coding rna
long noncoding rna
carbon dioxide
signaling pathway
transcription factor