Novel Coronavirus disease (COVID-19) in newborns and infants: what we know so far.
Domenico Umberto De RoseFiammetta PiersigilliMaria Paola RonchettiAlessandra SantisiIliana BersaniAndrea DottaOlivier DanhaiveCinzia Auritinull nullPublished in: Italian journal of pediatrics (2020)
Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successively designated 2019-nCoV then SARS-CoV-2). The SARS-CoV-2 causes a clinical syndrome designated coronavirus disease 2019 (COVID19) with a spectrum of manifestations ranging from mild upper respiratory tract infection to severe pneumonitis, acute respiratory distress syndrome (ARDS) and death. Few cases have been observed in children and adolescents who seem to have a more favorable clinical course than other age groups, and even fewer in newborn babies. This review provides an overview of the knowledge on SARS-CoV-2 epidemiology, transmission, the associated clinical presentation and outcomes in newborns and infants up to 6 months of life.
Keyphrases
- sars cov
- coronavirus disease
- acute respiratory distress syndrome
- respiratory syndrome coronavirus
- respiratory tract
- extracorporeal membrane oxygenation
- mechanical ventilation
- gestational age
- pregnant women
- healthcare
- interstitial lung disease
- cord blood
- low birth weight
- risk factors
- early onset
- intensive care unit
- rheumatoid arthritis
- metabolic syndrome
- case report
- systemic sclerosis
- adipose tissue
- idiopathic pulmonary fibrosis