High drug-loading gold nanoclusters for responsive glucose control in type 1 diabetes.

Yujie ZhangMingxin WuWubin DaiMin ChenZhaoyang GuoXin WangDi TanKui ShiLongjian XueSheng LiuYifeng Lei

Published in: Journal of nanobiotechnology (2019)

We successfully developed a phenylboronic acid-functionalized gold nanocluster system (AuNC-PBA-Ins) for responsive insulin release and glucose regulation in type 1 diabetes. This nanocluster system mimics the function of blood glucose regulation of pancreas in the body and may have potential applications in the theranostics of diabetes.

Keyphrases

blood glucose
glycemic control
type diabetes
cancer therapy
weight loss
insulin resistance
cardiovascular disease
silver nanoparticles
blood pressure
sensitive detection
quantum dots
fluorescent probe
label free
high resolution
solid phase extraction