Piezo1 Mediates Vasodilation Induced by Acute Hyperglycemia in Mouse Renal Arteries and Microvessels.

Lingyan FeiMinze XuHonghong WangCheng ZhongShan JiangFalk-Bach LichtenbergerCem ErdoğanHan WangJulia S Bonk En-Yin LaiPontus B PerssonRichard Kovács Zhihua Zheng Andreas Patzak Pratik H Khedkar

Published in: Hypertension (Dallas, Tex. : 1979) (2023)

Results reveal that Piezo1 mediates renal vasodilation induced by hyperosmolarity in acute hyperglycemia. This mechanism may contribute to the pathogenesis of renal damage by acute hyperglycemia.

Keyphrases

liver failure
respiratory failure
aortic dissection
drug induced
oxidative stress
diabetic rats
gene expression
single cell
genome wide
extracorporeal membrane oxygenation
dna methylation
mechanical ventilation