Immune checkpoint inhibitor-associated central nervous system autoimmunity.

Cristina Valencia SanchezElia SechiDivyanshu DubeyEoin Patrick FlanaganAndrew McKeonSean J Pittock Anastasia Zekeridou

Published in: European journal of neurology (2023)

One third of ICI-related CNS autoimmunity patients have unfavorable outcomes. Relapses may occur after ICI rechallenge. Neural autoantibodies are often present, more commonly in patients with NET.

Keyphrases

ejection fraction
newly diagnosed
systemic lupus erythematosus
prognostic factors
adipose tissue
cerebrospinal fluid
blood brain barrier
metabolic syndrome