Volatile organic compounds in breath can serve as a non-invasive diagnostic biomarker for the detection of advanced adenomas and colorectal cancer.
Kelly E van KeulenMaud E JansenRuud W M SchrauwenJeroen J KolkmanPeter Derk SiersemaPublished in: Alimentary pharmacology & therapeutics (2019)
This study suggests that exhaled VOCs could potentially serve as a non-invasive biomarker for the detection of CRC and AAs. Future studies including more patients could further improve the discriminatory potential of VOC analysis for the detection of (pre-)malignant colorectal lesions. (https://clinicaltrials.gov Identifier NCT03488537).