LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription.

Xin YinJingyan YangJintian ChenRuiqi NiYanhao ZhouHao SongLiang JinTingting TangYi Pan

Published in: Cancer cell international (2021)

Our data indicated that CTD-3252C9.4 could promote pancreatic cancer cell apoptosis and restrain cell growth via binding IRF1 and preventing the transcription of IFI6, which may become a potential therapeutic target for pancreatic cancer.

Keyphrases

transcription factor
oxidative stress
endoplasmic reticulum stress
cell proliferation
cell death
dendritic cells
electronic health record
big data
cell cycle arrest
immune response
dna binding
climate change
deep learning