Omalizumab response correlates with reduced IFN-γ-, IL-10- and IL-31-secreting cells in chronic spontaneous urticaria.
Michèle Myriam RauberJ PickertL HolianguChristian MöbsWolfgang PfütznerPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2020)
We here show that besides addressing IgE-dependent immune mechanisms, omalizumab treatment of CSU patients has effects on distinct T-cell subsets, which correlate with clinical improvement.