Induction of Macrophage M2b/c Polarization by Adipose Tissue-Derived Mesenchymal Stem Cells.

Meng SunLinxiao SunChongchu HuangBi-Cheng Chen Zhenxu Zhou

Published in: Journal of immunology research (2019)

ADMSCs can induce nonactivated macrophage and M1-Mφ into M2b/c-Mφ. Downregulation of the STAT3 and STAT6 pathway may involve in this process. This data shows that the anti-inflammatory role of ADMSC in local tissues may be partly due to their effect on Mφ to M2b/c-Mφ.

Keyphrases

adipose tissue
cell proliferation
anti inflammatory
insulin resistance
high fat diet
electronic health record
gene expression
signaling pathway
big data
type diabetes
machine learning
artificial intelligence