Login / Signup

The Diaphragm Acts as a Brake during Expiration to Prevent Lung Collapse.

Mariangela PellegriniGöran HedenstiernaAgneta RoneusMonica SegelsjöAnders LarssonGaetano Perchiazzi
Published in: American journal of respiratory and critical care medicine (2017)
The diaphragm is an important regulator of expiration. Its expiratory activity seems to preserve lung volume and to protect against lung collapse. The loss of diaphragmatic expiratory contraction during mechanical ventilation and muscle paralysis may be a contributing factor to unsuccessful respiratory support.
Keyphrases
  • mechanical ventilation
  • acute respiratory distress syndrome
  • intensive care unit
  • respiratory failure
  • extracorporeal membrane oxygenation
  • skeletal muscle
  • transcription factor