Significant increase of CTX-M-15-ST131 and emergence of CTX-M-27-ST131 Escherichia coli high-risk clones causing healthcare-associated bacteraemia of urinary origin in Spain (ITUBRAS-2 project).
Federico Becerra-AparicioInmaculada López MontesinosMarta Hernandez-GarcíaDesiré GijónAna SiverioDàmaris BerbelCarlos Sánchez-CarrilloEmilia CercenadoAlba RiveraAna de MaletMariona XercavinsEnrique Ruiz de GopeguiLuis Canoura-FernándezJosé Antonio MartínezCristina SeralJosé Luis Del PozoManuel CotareloJazmín Díaz-RegañónRafael CantónAntonio OliverJuan Pablo HorcajadaPatricia Ruiz-GarbajosaPublished in: The Journal of antimicrobial chemotherapy (2023)
ST131 HiRC is the main driver of ESBL-producing E. coli causing HCA-BUO in Spain, mainly associated with the expansion of subclade CTX-M-15-C2/H30-Rx and the emergence of CTX-M-27-C1/H30-R1 (Cluster C1-M27).