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Histology-based blood leukocyte profiling reveals parallel Th2 and Th17 signatures in seasonal allergic rhinitis.

Premkumar SiddhurajFranziska U NordströmPrajakta JogdandGayathri ElangovanMichiko MoriBjermer LeifLennart GreiffJonas S Erjefält
Published in: Acta oto-laryngologica (2022)
This study introduces a novel and applicable method for systemic immune cell screening and provides further evidence of complex and parallel Th2 and Th17-immune signatures in seasonal AR. It also forwards GATA2 and CPA3 as potential biomarkers for ongoing allergic inflammation.
Keyphrases
  • allergic rhinitis
  • genome wide
  • oxidative stress
  • transcription factor
  • single cell
  • peripheral blood