Histology-based blood leukocyte profiling reveals parallel Th2 and Th17 signatures in seasonal allergic rhinitis.

Premkumar Siddhuraj Franziska U NordströmPrajakta JogdandGayathri ElangovanMichiko MoriBjermer Leif Lennart Greiff Jonas S Erjefält

Published in: Acta oto-laryngologica (2022)

This study introduces a novel and applicable method for systemic immune cell screening and provides further evidence of complex and parallel Th2 and Th17-immune signatures in seasonal AR. It also forwards GATA2 and CPA3 as potential biomarkers for ongoing allergic inflammation.

Keyphrases

allergic rhinitis
genome wide
oxidative stress
transcription factor
single cell
peripheral blood