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Bioluminescence Imaging In Vivo Confirms the Viability of Pancreatic Islets Transplanted into the Greater Omentum.

Zuzana HladíkováBarbora VoglováAlžběta PátíkováZuzana BerkováJan KřížAlžběta VojtíškováIvan LeontovyčDaniel JirákFrantišek Saudek
Published in: Molecular imaging and biology (2021)
We successfully tested a preclinical model of islet transplantation into the greater omentum using a biocompatible scaffold made from autologous plasma and human thrombin. Both standard and marginal pancreatic islet numbers in a gel-form bioscaffold placed in the omentum restored glucose homeostasis in recipients with diabetes. Bioluminescence was shown promising as a direct proof of islet viability.
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