Association between long-term exposure to air pollution and immune-mediated diseases: a population-based cohort study.

Giovanni AdamiMarco PontaltiGiorgio CattaniMaurizio RossiniOmbretta ViapianaGiovanni OrsoliniCamilla BeniniEugenia BertoldoElena FracassiDavide GattiAngelo Fassio

Published in: RMD open (2022)

Long-term exposure to air pollution was associated with higher risk of developing autoimmune diseases, in particular rheumatoid arthritis, CTDs and IBD. Chronic exposure to levels above the threshold for human protection was associated with a 10% higher risk of developing IMIDs.

Keyphrases

air pollution
rheumatoid arthritis
particulate matter
endothelial cells
lung function
disease activity
induced pluripotent stem cells
ankylosing spondylitis
systemic lupus erythematosus
ulcerative colitis