Extreme acute radiation-induced toxicity in a patient with polymorphous low-grade adenocarcinoma of the nasopharynx and rare variants in DNA repair genes.
Zuzanna NowickaKasper KunaKonrad StawiskiJulia SołekMagdalena ŚwiderekAnna Papis-UbychJacek FijuthWojciech FendlerBartłomiej TomasikPublished in: Head & neck (2023)
Genetic causes should be considered in cases of extreme radiosensitivity, especially when is not explained by clinical factors.
Keyphrases
- low grade
- radiation induced
- dna repair
- high grade
- genome wide
- dna damage
- copy number
- radiation therapy
- climate change
- liver failure
- dna damage response
- case report
- squamous cell carcinoma
- respiratory failure
- oxidative stress
- locally advanced
- drug induced
- dna methylation
- gene expression
- hepatitis b virus
- rectal cancer
- extracorporeal membrane oxygenation
- intensive care unit
- mechanical ventilation