NLRP1 activation by UVB: Shedding light on an enigmatic inflammasome.
Andrew SandstromPublished in: The Journal of experimental medicine (2022)
In this issue of JEM, Jenster et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20220837) investigate how UVB radiation promotes activation of the inflammatory immune sensor NLRP1, and in doing so uncover how NLRP1 recognizes a diverse range of ribotoxic stresses.
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