Neuroblastic tumors in young adults as a sequela of malignant neuroblastoma: report of two cases.
Takuya AdachiMinato YokoyamaYasuhisa FujiiYuko KinowakiSusumu KirimuraKazunori KubotaYukihisa SaidaUkihide TateishiPublished in: Abdominal radiology (New York) (2019)
Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma share the same histological spectrum which originates from neural crest cells. We present herein two young adult patients with neuroblastic tumors with lymph node metastases. Both the patients were diagnosed incidentally as having retroperitoneal masses, which showed little or no immature cells despite coexistence of lymph node involvement. The tumors were considered to represent spontaneous regression of malignant neuroblastoma. Radiologists should consider the possibility of spontaneous regression of neuroblastic tumors, when poorly enhanced multi-component masses at the retroperitoneum with lymph node involvement are visualized.
Keyphrases
- lymph node
- induced apoptosis
- young adults
- neoadjuvant chemotherapy
- cell cycle arrest
- sentinel lymph node
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- endoplasmic reticulum stress
- oxidative stress
- signaling pathway
- machine learning
- computed tomography
- radiation therapy
- contrast enhanced
- fine needle aspiration
- minimally invasive
- rectal cancer
- locally advanced