Liver dysfunction in idiopathic pulmonary arterial hypertension: prevalence, characteristics and prognostic significance, a retrospective cohort study in China.

Ci-Jun LuoWenhui WuChangwei WuHongling QiuPing YuanRong JiangQinhua ZhaoSugang GongRui ZhangJinling LiJing HeJinming LiuLan Wang

Published in: BMJ open (2021)

Liver dysfunction is frequent in IPAH, and characterised by a predominantly cholestatic enzyme profile. LFTs abnormalities are associated with worse survival and LFPI was a new and simple predictor for prognosis of IPAH.

Keyphrases

pulmonary arterial hypertension
pulmonary artery
pulmonary hypertension
oxidative stress
risk factors
liver injury
liver fibrosis
free survival
drug induced