Central 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Jin-Seok LeeJi-Yun KangSamuel-Young ParkSeung-Ju HwangSung-Jin BaeChang-Gue SonPublished in: Journal of translational medicine (2024)
Our findings support the involvement of 5-HTergic hyperactivity in the pathophysiology of ME/CFS. This ME/CFS-mimicking animal model would be useful for understanding ME/CFS biology and its therapeutic approaches.
Keyphrases