MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway.
Yu YangPei ZhangRuicheng YanQi WangErhu FangHongxue WuShijun LiHaiyan TanXing ZhouXianxiong MaYu TangYongming HuangRui DengYing LiuShilun TongZhihua WangRebecca E Oberley-DeeganQiang TongPublished in: Oxidative medicine and cellular longevity (2019)
Taken together, we provide an in-depth mechanism by which MnTE-2-PyP inhibits colorectal cancer progression, supporting an important role for MnTE-2-PyP as an effective and innovative antitumor agent to enhance treatment outcomes in colorectal cancer.