Blood biomarkers for the differentiation between central and peripheral vertigo in the emergency department: a systematic review and meta-analysis.

Vincent W KlokmanFiona N KoningsteinJob W W DorsMarieke S SandersSam W KoningDominique P V de KleijnKim E Jie

Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2024)

This systematic review and meta-analysis highlights the potential of generalized inflammatory markers and brain-specific blood protein markers of NSE and S100β as diagnostic biomarkers for central from peripheral differentiation in AVS. These results, as a complement to clinical characteristics, provide guidance for future large-scale diagnostic research, in this challenging ED patient population.

Keyphrases

emergency department
chemotherapy induced
case report
current status
resting state
risk assessment
protein protein
functional connectivity
multiple sclerosis
blood brain barrier