Inflammation, diet, and type 2 diabetes: a mini-review.
Simin JafaripourSima SedighiMohammad Hassan JokarMehrdad AghaieMaliheh MoradzadehPublished in: Journal of immunoassay & immunochemistry (2020)
Inflammation is a common feature of type 2 diabetes (T2D). Inflammatory cytokines increase in patients with type 2 diabetes, metabolic syndrome, and heart disease. Various types of cells can produce inflammatory cytokines and then release them into the bloodstream, where their complex interactions with target tissues raise a tissue-specific immune response. This review focused on C-reactive protein (CRP), tumor necrosis factor (TNF)-α as an inflammatory cytokine, and adiponectin produced by adipose tissues. Despite the major role of cytokines in the development of T2D, further studies are required to investigate the possible effects of the macronutrient composition of diet on these cytokines.
Keyphrases
- type diabetes
- metabolic syndrome
- insulin resistance
- oxidative stress
- immune response
- induced apoptosis
- rheumatoid arthritis
- glycemic control
- physical activity
- gene expression
- weight loss
- adipose tissue
- cardiovascular disease
- machine learning
- cell cycle arrest
- deep learning
- pulmonary hypertension
- dendritic cells
- cardiovascular risk factors
- toll like receptor
- signaling pathway
- escherichia coli
- inflammatory response
- case control
- klebsiella pneumoniae