Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials.

Jimi HuhSu Jung HamYoung Chul ChoBumwoo ParkBohyun KimChul-Woong WooYoonseok ChoiDong-Cheol WooKyoung Won Kim

Published in: BMC medical imaging (2019)

Among the gadoxetate-enhanced DCE-MRI indices, iAUC-15 and iAUC-3 might be bidirectional translatable biomarkers between preclinical and clinical research for evaluating histopathologic liver fibrosis and physiologic liver functions in a non-invasive manner.

Keyphrases

liver fibrosis
contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
magnetic resonance
computed tomography
stem cells