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Gadoxetate-enhanced dynamic contrast-enhanced MRI for evaluation of liver function and liver fibrosis in preclinical trials.

Jimi HuhSu Jung HamYoung Chul ChoBumwoo ParkBohyun KimChul-Woong WooYoonseok ChoiDong-Cheol WooKyoung Won Kim
Published in: BMC medical imaging (2019)
Among the gadoxetate-enhanced DCE-MRI indices, iAUC-15 and iAUC-3 might be bidirectional translatable biomarkers between preclinical and clinical research for evaluating histopathologic liver fibrosis and physiologic liver functions in a non-invasive manner.
Keyphrases
  • liver fibrosis
  • contrast enhanced
  • magnetic resonance imaging
  • diffusion weighted imaging
  • magnetic resonance
  • computed tomography
  • stem cells