Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture.

Oscar MaldonadoAlexandra JenkinsHelen M BelalcazarHelena Hernandez-CuervoKatelynn M HymanGiannina LadagaLucia PadillaGabriel A de Erausquin

Published in: PloS one (2020)

The effects of the SK3 channel agonist 1-EBIO on the survival of SK3-expressing dopaminergic neurons were concentration-dependent and influenced by neuronal developmental stage.

Keyphrases

spinal cord
cerebral ischemia
free survival
subarachnoid hemorrhage
brain injury
blood brain barrier