Intracardiac thrombosis following intravenous zoledronate treatment in a child with steroid-induced osteoporosis.
Samantha J CaseRebecca Jane MoonTara BharuchaJustin Huw DaviesPublished in: Journal of pediatric endocrinology & metabolism : JPEM (2022)
Potential causes for intracardiac thrombosis in this patient include ventricular dysfunction due to acute adrenal crisis or electrolyte disturbance, and hypercoagulability due to the APR. Echocardiography should be considered in children with acute cardiovascular compromise following zoledronate. Stress-dose steroids to cover the APR and a reduced starting dose of zoledronate might have reduced the risk of this complication.
Keyphrases
- pulmonary embolism
- left ventricular
- drug induced
- left atrial appendage
- liver failure
- public health
- heart failure
- postmenopausal women
- computed tomography
- case report
- mental health
- high glucose
- bone mineral density
- respiratory failure
- diabetic rats
- ionic liquid
- aortic dissection
- combination therapy
- risk assessment
- stress induced
- atrial fibrillation
- intensive care unit
- human health
- catheter ablation