Mechanism Prediction of Astragalus membranaceus against Cisplatin-Induced Kidney Damage by Network Pharmacology and Molecular Docking.

Congchao Jia Xianchao Pan Binyou Wang Pengyu Wang Yiwei Wang Rong Chen

Published in: Evidence-based complementary and alternative medicine : eCAM (2021)

In summary, the active components, key targets, and signaling pathways of AM in the treatment of cisplatin-induced kidney damage were predicted in this study, which contributed to the development and application of AM.

Keyphrases

molecular docking
oxidative stress
molecular dynamics simulations
signaling pathway
epithelial mesenchymal transition
combination therapy
cell proliferation
network analysis