Use of intraoperative frontal sinus mometasone-eluting stents decreased interleukin 5 and interleukin 13 in patients with chronic rhinosinusitis with nasal polyps.
Alexander L SchneiderSamuel D RacetteAnthony K KangAbhita T ReddyJulia H HuangDavid S LehmannCaroline P E PriceJacob G EideSamuel R RodeghieroDavid B ConleyKevin C WelchRobert C KernStephanie Shintani SmithAnju T PetersAtsushi KatoWhitney W StevensRobert P SchleimerBruce K TanPublished in: International forum of allergy & rhinology (2022)
Although patients who received intraoperative frontal MES had significantly higher pre-ESS MM IL-13 and ECP, patients who received frontal MES had lower concentrations of IL-4 and IL-13 than those who did not at a median of 8 months post-ESS. However, these changes did not correspond to significantly different measures of symptomatic or radiographic disease severity.