Analysis of urinary sphingolipids using liquid chromatography-tandem mass spectrometry in diabetic nephropathy.

Yoshifumi MoritaMakoto KuranoEri SakaiTakako NishikawaMasako NishikawaMotoji SawabeJunken AokiYutaka Yatomi

Published in: Journal of diabetes investigation (2019)

Our method is useful for the measurement of ceramide in urine specimens, and urinary ceramides might be associated with the pathological condition of diabetic nephropathy, such as renal tubular injury.

Keyphrases

diabetic nephropathy
liquid chromatography tandem mass spectrometry
simultaneous determination
ms ms
solid phase extraction
tandem mass spectrometry
high glucose
high resolution