Cervical Precancers and Cancers Attributed to HPV Types by Race and Ethnicity: Implications for Vaccination, Screening, and Management.
Jacqueline M MixMona SaraiyaBenjamin D HallowellBrian BefanoLi C CheungElizabeth R UngerJulia W GarganoLauri E MarkowitzPhilip E CastleTina Raine-BennettJoan L WalkerRosemary ZunaMark SchiffmanNicolas WenstzensenJulia C GagePublished in: Journal of the National Cancer Institute (2022)
The 9-valent HPV vaccine will prevent nearly all cervical precancers and invasive cancers among major racial and ethnic groups in the United States. Adding HPV35 to vaccines could prevent a small percentage of CIN3s and SCCs, with greater potential impact for CIN3s among Black women. HPV screening tests target high-risk HPV types, including HPV35. Future genotyping triage strategies could consider the importance of HPV35- and other HPV16-related types.