Gastric ghrelin cells in obese patients are hyperactive.
Sergio CastorinaVincenza BarresiTonia LucaGiovanna PriviteraVincenzo De GeronimoGiovanni LezocheIlaria CosentiniAngelica Di VincenzoGiorgio BarbatelliAntonio GiordanoMarina TausAlbano NicolaiDaniele Filippo CondorelliSaverio CintiPublished in: International journal of obesity (2005) (2020)
Given the known inhibitory role on insulin secretion of ghrelin, these results suggest a possible role for gastric ghrelin overproduction in the complex architecture that takes part in the pathogenesis of type 2 diabetes.