Gastric ghrelin cells in obese patients are hyperactive.

Sergio CastorinaVincenza BarresiTonia LucaGiovanna PriviteraVincenzo De GeronimoGiovanni LezocheIlaria CosentiniAngelica Di VincenzoGiorgio BarbatelliAntonio GiordanoMarina TausAlbano NicolaiDaniele Filippo CondorelliSaverio Cinti

Published in: International journal of obesity (2005) (2020)

Given the known inhibitory role on insulin secretion of ghrelin, these results suggest a possible role for gastric ghrelin overproduction in the complex architecture that takes part in the pathogenesis of type 2 diabetes.

Keyphrases

obese patients
bariatric surgery
induced apoptosis
roux en y gastric bypass
gastric bypass
cell cycle arrest
cell death
signaling pathway
cell proliferation
pi k akt