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Gastric ghrelin cells in obese patients are hyperactive.

Sergio CastorinaVincenza BarresiTonia LucaGiovanna PriviteraVincenzo De GeronimoGiovanni LezocheIlaria CosentiniAngelica Di VincenzoGiorgio BarbatelliAntonio GiordanoMarina TausAlbano NicolaiDaniele Filippo CondorelliSaverio Cinti
Published in: International journal of obesity (2005) (2020)
Given the known inhibitory role on insulin secretion of ghrelin, these results suggest a possible role for gastric ghrelin overproduction in the complex architecture that takes part in the pathogenesis of type 2 diabetes.
Keyphrases
  • obese patients
  • bariatric surgery
  • induced apoptosis
  • roux en y gastric bypass
  • gastric bypass
  • cell cycle arrest
  • cell death
  • signaling pathway
  • cell proliferation
  • pi k akt