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Cytotoxic activity of the chloroform fraction of Piper aduncum and its effect on the cell cycle in gastric cancer cell lines.

Ana Mayanga-HerreraSalyoc Tapia-RojasAlejandro Fukusaki-YoshizawaÁlvaro Marcelo-RodríguezJosé Amiel-Pérez
Published in: Revista peruana de medicina experimental y salud publica (2021)
PAMoCl contains secondary metabolites with cytotoxic activity that have an effect on the G2/M phase of the cell cycle, in two gastric cancer cell lines, both primary and metastatic. The results of this study will allow us to deepen the search for more effective active ingredients found in PAMoCl for eliminating gastric cancer cells, but with less toxicity for healthy cells.
Keyphrases
  • cell cycle
  • cell proliferation
  • induced apoptosis
  • squamous cell carcinoma
  • small cell lung cancer
  • cell cycle arrest
  • oxidative stress
  • ms ms
  • cell death
  • signaling pathway
  • oxide nanoparticles