Quantitative and semi-quantitative computed tomography analysis of interstitial lung disease associated with systemic sclerosis: A longitudinal evaluation of pulmonary parenchyma and vessels.
Mariaelena OcchipintiSilvia BoselloLeuconoe Grazia SistiGiuseppe CicchettiChiara de WaureTommaso PirrontiGianfranco FerraccioliElisa GremeseAnna Rita LariciPublished in: PloS one (2019)
Pulmonary QA of CT images can objectively quantify specific patterns of ILD changes during treatment in patients with SSc-ILD. Changes in QA patterns do not correlate with functional changes, but variation in total lung volume at QA accurately predicted changes in the composite functional respiratory endpoint with FVC% and DLco%. Pulmonary artery diameter at CT reflects the interstitial involvement, identifying patients with more severe prognosis.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- pulmonary hypertension
- pulmonary artery
- computed tomography
- dual energy
- image quality
- contrast enhanced
- pulmonary arterial hypertension
- positron emission tomography
- coronary artery
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- high resolution
- magnetic resonance imaging
- physical activity
- convolutional neural network
- deep learning
- optical coherence tomography
- machine learning
- early onset
- magnetic resonance