Periodontal disease in patients with WHIM syndrome.
Laurie BrenchleyDavid H McDermottPamela J GardnerLakmali M SilvaJi-Liang GaoElena ChoDaniel VelezNiki M MoutsopoulosPhilip M MurphyDavid FraserPublished in: Journal of clinical periodontology (2024)
Overall, WHIM syndrome patients presented with an increased severity of periodontitis despite past and ongoing neutrophil mobilization treatments. GOF mutations in CXCR4 may be a risk factor for periodontitis in humans.