The Role of Hydrogen Sulfide Regulation of Autophagy in Liver Disorders.

Autophagy is a complex process of degradation of senescent or dysfunctional organelles in cells. Dysfunctional autophagy is associated with many diseases such as cancers, immune dysfunction, and aging. Hydrogen sulfide (H 2 S) is considered to be the third gas signal molecule after nitrous oxide and carbon monoxide. In recent years, H 2 S has been found to have a variety of important biological functions, and plays an important role in a variety of physiological and pathological processes. In this review, we review the recent role and mechanism of H 2 S in regulating autophagy in liver disorders, in order to provide a basis for further research in the future.