Multidisciplinary and Tailored Treatment of Locally Advanced Breast Cancer in Progression during Neoadjuvant Chemotherapy: Case Report.
Letizia CunioloMarco GipponiFederica MurelliFrancesca DepaoliChiara CornacchiaSimonetta FranchelliMarianna PesceElena RondaStefano PicardiRaquel DiazFrancesca PoggioDaniele FriedmanFranco De CianPiero FregattiPublished in: Current oncology (Toronto, Ont.) (2024)
Locally advanced breast cancer (LABC) is a complex disease that requires a multidisciplinary approach. Neoadjuvant chemotherapy (NAC) is usually performed in order to achieve loco-regional radical resection; although its importance in the multidisciplinary approach to LABC is well recognized, a small number of patients show Progressive Disease (PD). No standard salvage treatment (ST) has been defined and different strategies can be adopted, such as second-line systemic therapies, radiation therapy, and surgery. Herein, a case of LABC in PD during NAC is reported with a literature review, with the aim of highlighting the importance of a tailored multidisciplinary treatment for each patient.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- radiation therapy
- case report
- rectal cancer
- squamous cell carcinoma
- lymph node
- sentinel lymph node
- phase ii study
- minimally invasive
- multiple sclerosis
- quality improvement
- end stage renal disease
- early stage
- clinical trial
- coronary artery bypass
- peritoneal dialysis
- percutaneous coronary intervention
- prognostic factors
- young adults