Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma.
Jian-An JiaShuqin ZhangXin BaiMeng FangShipeng ChenXiaotao LiangShanfeng ZhuDanny Ka-Ho WongAnye ZhangJianfeng FengFengzhu SunChunfang GaoPublished in: Virology journal (2022)
Using NGS and SLR, the association between HBV preS region nucleotide entropy and HCC development was validated in our study and this could promote the understanding of HCC progression mechanism.