Elastase and exacerbation of neutrophil innate immunity are involved in multi-visceral manifestations of COVID-19.

Jean-Louis GuéantRosa-Maria Guéant-RodriguezJulien FromonotAbderrahim OussalahHuguette LouisCeline CheryMickael GetteStanislas GleyeJonas CalletJeremie RasoFrançois BlanchecottePatrick LacolleyRégis GuieuVéronique Regnault

Published in: Allergy (2021)

Our results point out the key role of neutrophil innate immunity exacerbation in COVID-19. Neutrophil elastase and DNase could be potential biomarkers and therapeutic targets of severe systemic manifestations of COVID-19.

Keyphrases

coronavirus disease
sars cov
chronic obstructive pulmonary disease
insulin resistance
early onset
intensive care unit
metabolic syndrome
adipose tissue