Specific bacterial co-abundance groups are associated with inflammatory status in patients with ulcerative colitis.

Sushrut JangiNaisi ZhaoKatie HsiaYoung Soo ParkDominique S MichaudHyuk Yoon

Published in: Journal of Crohn's & colitis (2024)

Lachnospiriceae-dominated bacterial CAGs were associated with remission in UC, with key bacterial interactions within the CAG also observed in 2 healthy cohorts and a Korean UC cohort. Bacterial CAG-based analyses may help to inform the design of candidate consortia for microbiome-based therapeutics.

Keyphrases

ulcerative colitis
oxidative stress
small molecule
rheumatoid arthritis
systemic lupus erythematosus
disease activity
microbial community
wastewater treatment